Thermo Fisher Scientific Kininogen Heavy Chain Monoclonal Antibody (2B5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-10 µg/mL

-

ELISA (ELISA)

1-10 µg/mL

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2B5

Immunogen

Purified high molecular weight kininogen. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Kininogen Heavy Chain,uniProtId:P01042-1,ncbiNodeId:9606,antigenRange:1-644,antigenLength:644,antigenImageFileName:MA1-10832_Kininogen_Heavy_Chain_P01042-1_House_mouse.svg,antigenImageFileNamePDP:MA1-10832_Kininogen_Heavy_Chain_P01042-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1076361

Product Specific Information

MA1-10832 detects High MW Kininogen, heavy chain, from human samples.

MA1-10832 has been successfully used in ELISA and Western blot applications.

The MA1-10832 immunogen is purified high molecular weight kininogen.

Target Information

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.