Thermo Fisher Scientific IGF1R alpha Monoclonal Antibody (2C8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2C8

Immunogen

Purified human placental IGF-1 receptors. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IGF1R alpha,uniProtId:P08069-1,ncbiNodeId:9606,antigenRange:1-1367,antigenLength:1367,antigenImageFileName:MA1-10855_IGF1R_alpha_P08069-1_House_mouse.svg,antigenImageFileNamePDP:MA1-10855_IGF1R_alpha_P08069-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

purified

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1075415

Product Specific Information

MA1-10855 detects IGF-1 Receptor from human samples.

MA1-10855 has been successfully used in Western blot applications.

The MA1-10855 immunogen is purified human placental IGF-1 receptors.

Target Information

IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of malignant cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.