Thermo Fisher Scientific IGF1R alpha Monoclonal Antibody (2C8)
Human IGF1R alpha 단백질을 인식하는 Mouse monoclonal antibody. Western blot에 최적화되어 있으며, 고순도 정제된 형태로 제공. PBS buffer에 보존되어 있으며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C8 |
| Immunogen | Purified human placental IGF-1 receptors |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075415 |
Product Specific Information
MA1-10855 detects IGF-1 Receptor from human samples.
It has been successfully used in Western blot applications.
The immunogen is purified human placental IGF-1 receptors.
Target Information
IGF1R (Insulin-like Growth Factor 1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IGF1).
It binds IGF1 with high affinity and IGF2/insulin with lower affinity.
Activated IGF1R is involved in cell growth and survival control, crucial for tumor transformation and survival of malignant cells.
Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosine phosphorylation of multiple substrates that function as signaling adapter proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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