Thermo Fisher Scientific HEXB Polyclonal Antibody
HEXB 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P)에서 검증됨. E.coli 유래 인간 HEXB 재조합 단백질로부터 제작. 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human HEXB recombinant protein (Position: K381–M556) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746475 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Hexosaminidase B (HEXB), also designated beta-hexosaminidase B, is a tetramer of two β-A and two β-B chains localized in lysosomes. Mutations in the HEXB gene cause Sandhoff disease (GM2-gangliosidosis type II), an autosomal recessive disorder leading to accumulation of GM2 ganglioside and progressive destruction of the central nervous system. This condition is more severe than Tay-Sachs disease, which results from mutations in the HEXA gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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