Thermo Fisher Scientific IL23R Polyclonal Antibody
IL23R 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 인간, 마우스, 랫트에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS 버퍼에 50% 글리세롤 함유, -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IL23R (Accession Q5VWK5), corresponding to amino acid residues T40–K90. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851846 |
Product Specific Information
Antibody detects endogenous levels of total IL23R.
Target Information
IL-23R is a 629 amino acid subunit of the receptor for cytokine IL23A/IL23, which pairs with IL12RB1 (IL12R beta 1) to mediate IL23A signaling. It constitutively associates with Janus kinase 2 (JAK2) and binds to transcription activator STAT3 in a ligand-dependent manner.
Alternative splicing results in six isoforms of IL-23R. IL-23R is implicated in psoriasis pathogenesis and is a potential therapeutic target in inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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