Thermo Fisher Scientific KPNA2 Polyclonal Antibody
KPNA2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin)에서 검증됨. Human, Mouse, Rat에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며, 연구용으로 적합.
- 카탈로그번호
- PA5102445
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KPNA2 (Accession P52292), corresponding to amino acid residues D44–L94 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851850 |
Product Specific Information
Antibody detects endogenous levels of total KPNA2.
Target Information
The import of proteins into the nucleus involves two main steps:
- An energy-independent docking of the protein to the nuclear envelope.
- An energy-dependent translocation through the nuclear pore complex.
Imported proteins require a nuclear localization sequence (NLS), typically a short region of basic amino acids or two such regions spaced about 10 amino acids apart. Proteins involved in the initial step of nuclear import include the Xenopus protein importin and its yeast homolog SRP1, which bind to the NLS.
KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in nuclear protein transport. It may also play a role in VJ recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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