Thermo Fisher Scientific TLR10 Polyclonal Antibody
TLR10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(Paraffin)에서 검증됨. 인간 TLR10 N-말단 합성 펩타이드 기반 면역원 사용. 4°C 보관, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 1–100 of an N-terminal portion of human TLR10 (Swiss-Prot# Q9BXR5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2204293 |
Product Specific Information
- The target sequence has 90% sequence homology with bovine.
- Suggested positive control: antigen standard for TLR10 (transient overexpression lysate), Ramos whole cell extracts.
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity.
TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.
They recognize pathogen-associated molecular patterns (PAMPs) expressed on infectious agents and mediate cytokine production necessary for effective immunity.
TLR10 is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil.
Its exact function remains unknown. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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