Thermo Fisher Scientific LMO2 Polyclonal Antibody
LMO2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ChIP 등 다양한 응용에 적합. Human, Mouse, Rat, Bovine 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250–1:500 |
| ChIP assay (ChIP) | 1:10–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 1–100 of an N-terminal portion of human LMO2 (Swiss-Prot# P25791) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2136561 |
Product Specific Information
- The target sequence has 93% sequence homology with zebrafish.
- Suggested positive control: Ramos whole cell extracts.
Target Information
LMO2 encodes a cysteine-rich, two LIM-domain protein required for yolk sac erythropoiesis. The LMO2 protein plays a central and crucial role in hematopoietic development and is highly conserved. The transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where several T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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