Thermo Fisher Scientific Phospho-Cdc25A (Ser79) Polyclonal Antibody
인간 Cdc25A 단백질의 Ser79 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Dot blot에서 검증됨. Protein A 및 항원 친화 크로마토그래피로 정제. PBS(pH 7.4) 완충액에 0.09% sodium azide 포함. 단기 4°C, 장기 -20°C 보관.
- 카탈로그번호
- PA512951
- 판매단위
- pk
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Applications
- Dot blot (DB)
Tested Dilution: 1:500
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S79 of human Cdc25A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10988834 |
Product Specific Information
This antibody is predicted to react with bovine, mouse, and rat based on sequence homology.
Target Information
CDC25A is a member of the CDC25 family of phosphatases. Three CDC25 genes (CDC25A, CDC25B, CDC25C) are present in human cells and function at different phases of the cell cycle.
CDC25A is required for progression through G1 and S phases by activating cyclin-dependent kinase CDC2 through dephosphorylation.
CDC25A is specifically degraded in response to DNA damage, preventing abnormal cells from dividing. It is considered an oncogene, though its precise role in oncogenesis remains unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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