Thermo Fisher Scientific Aquaporin 0 Polyclonal Antibody
Aquaporin 0 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 제품. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: [참조 없음]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [참조 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 110–160 of human AQP0 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553576 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 28 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
AQP0 is the most abundant endogenous protein in the plasma membrane of lens fiber cells. It functions as a water pore and plays a role in fiber-fiber adhesion, crucial for fiber cell structure and organization.
AQP0 contains an additional pore constriction not seen in other aquaporins, possibly responsible for pore gating. The closed AQP0 pore holds three water molecules spaced too far apart to form hydrogen bonds.
Its C-terminal domain undergoes extensive post-translational modifications, including truncations during lens aging, which may contribute to cataract development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-36535_Aquaporin_0_P30301-1_Rabbit.svg, PA5-36535_Aquaporin_0_P30301-1_Rabbit_PDP.jpeg)
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