Thermo Fisher Scientific CaV3.1 Monoclonal Antibody (N178A/9), PE
CaV3.1 단백질을 검출하기 위한 PE-결합 마우스 단클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. 사람, 생쥐, 랫트에 반응하며, 단백질 G로 정제된 액상 형태. 565/576 nm 형광 특성을 가지며, 4°C에서 보관.
- 카탈로그번호
- MA545546
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N178A/9 |
| Immunogen | Fusion protein amino acids 2052–2172 (cytoplasmic C-terminus) of mouse Cav3.1 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932000 |
Available Formats
- Unconjugated (MA5-27655)
- APC (MA5-45543)
- FITC (MA5-45544)
- PerCP (MA5-45545)
- Request custom conjugation
Product Specific Information
1 µg/mL of MA5-45546 was sufficient for detection of Cav3.1 in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately <200 kDa. Does not cross-react with Cav3.2.
This antibody was formerly sold as clone S178A-9.
Target Information
Voltage-dependent Ca²⁺ channels mediate Ca²⁺ entry into excitable cells in response to membrane depolarization and are involved in muscle contraction, hormone or neurotransmitter release, and gene expression. These channels are multimeric complexes composed of an alpha-1 subunit, intracellular beta subunit, disulfide-linked alpha-2/delta subunit, and transmembrane gamma subunit.
T-type Ca²⁺ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca²⁺ current types. They enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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