Thermo Fisher Scientific CaV3.1 Monoclonal Antibody (N178A/9), PerCP
CaV3.1 단백질을 검출하기 위한 PerCP 결합 단클론 항체로, WB, IHC, ICC에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Protein G 정제, 1 mg/mL 농도. 482/675 nm 형광 특성으로 정밀한 세포 분석에 적합.
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Thermo Fisher Scientific CaV3.1 Monoclonal Antibody (N178A/9), PerCP
Applications and Tested Dilutions
- Western Blot (WB): 1:1,000
- Immunohistochemistry (IHC): Assay-dependent
- Immunocytochemistry (ICC/IF): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N178A/9 |
| Immunogen | Fusion protein amino acids 2052–2172 (cytoplasmic C-terminus) of mouse Cav3.1 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931999 |
Additional Formats
Product Specific Information
1 µg/mL of MA5-45545 was sufficient for detection of Cav3.1 in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately <200 kDa. Does not cross-react with Cav3.2.
This antibody was formerly sold as clone S178A-9.
Target Information
Voltage-dependent Ca²⁺ channels mediate calcium entry into excitable cells in response to membrane depolarization. They participate in various Ca²⁺-dependent processes such as muscle contraction, hormone or neurotransmitter release, and gene expression.
Calcium channels are multimeric complexes composed of:
- α1 subunit
- intracellular β subunit
- disulfide-linked α2/δ subunit
- transmembrane γ subunit
Ca²⁺ currents are classified by biophysical and pharmacologic properties: L-, N-, T-, P-, Q-, and R-types.
T-type Ca²⁺ currents are activated and inactivated more rapidly and at lower membrane potentials than other types.
T-type channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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