
Thermo Fisher Scientific Phospho-p70 S6 Kinase (Thr421, Ser424) Recombinant Superclonal Antibody (B12HCLC)
인간 p70 S6 Kinase의 Thr421, Ser424 인산화 부위를 인식하는 재조합 Superclonal™ 항체입니다. WB 및 ICC/IF에 적합하며, 높은 특이성과 재현성을 제공합니다. Protein A로 정제되어 0.5 mg/mL 농도로 제공되며, 장기 보관 시 -20°C에서 안정적입니다.
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Thermo Fisher Scientific Phospho-p70 S6 Kinase (Thr421, Ser424) Recombinant Superclonal Antibody (B12HCLC)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | B12HCLC |
| Immunogen | Phosphopeptide corresponding to amino acids 417–428 of human p70 S6K |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532567 |
Product Specific Information
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
These antibodies recognize multiple epitope sites on the target, providing high detection sensitivity for low-abundance targets. Each lot contains a defined mixture of light and heavy chains, ensuring reproducibility and eliminating biological variability found in traditional polyclonal antibody production.
Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.
Target Information
RPS6KB1 (p70S6K) is a serine/threonine kinase with two non-identical catalytic domains that phosphorylates several residues of the S6 ribosomal protein. It is predominantly localized in the cytoplasm and plays essential roles in cell growth, proliferation, motility, immune response, and tissue repair.
p70 S6 kinase acts downstream of PI3-kinase, with the S6 ribosomal protein as its main physiological target, promoting protein synthesis and cell proliferation. Amplification and overexpression of p70 S6 kinase are observed in certain breast cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 710108_p70_S6_Kinase_P23443-1_Rabbit.svg, 710108_p70_S6_Kinase_P23443-1_Rabbit_PDP.jpeg)
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