
Thermo Fisher Scientific CD9 Monoclonal Antibody (MM2/57)
CD9 단백질을 인식하는 마우스 모노클로날 항체로, 다양한 종에 반응하며 WB, IHC, Flow Cytometry 등 다중 응용에 사용 가능. Protein G 정제, PBS 완충액에 0.09% sodium azide 포함. 세포 표면 단백질 연구 및 세포 신호전달 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | 8 publications |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:500–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
| Flow Cytometry (Flow) | 1:100–1:200 | 2 publications |
| Immunoprecipitation (IP) | - | 2 publications |
| Miscellaneous PubMed (Misc) | - | 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Horse, Cat, Human, Mink, Pig, Rabbit, Rhesus monkey |
| Published Species | Human, Mouse, Pig, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MM2/57 |
| Immunogen | Human platelet membrane (Target: CD9, UniProt ID: P21926-1, Range: 1–228) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; -20°C long term (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_929680 |
Additional Formats
Product Specific Information
- Predicted to react with mustelid based on sequence homology.
- For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
- Mouse anti-Human CD9 antibody, clone MM2/57, recognizes human leukocyte antigen MIC3 (also known as MRP-1 or CD9).
Target Information
CD9 antigen is a glycoprotein expressed on developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, neurons, and glial cells.
It belongs to the tetraspanin family, spanning the membrane four times. In pre-B cells and platelets, CD9 regulates activation and aggregation, possibly through association with integrin CD41/CD61 (GPIIb/GPIIIa).
CD9 is involved in:
- Cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, sperm-egg fusion
- Cell attachment, proliferation, and differentiation
- Association of heterologous MHC II molecules on dendritic cells for effective T cell stimulation
- Suppression of cancer cell motility and metastasis (acts as a metastasis suppressor in solid tumors)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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