Thermo Fisher Scientific WASP Recombinant Rabbit Monoclonal Antibody (ARC1204)
WASP 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody로, Western Blot, Immunocytochemistry, ELISA에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 고순도 Affinity Chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1204 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human WASP (P42768) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849556 |
Product Specific Information
Immunogen sequence:
MSGGPMGGRP GGRGAPAVQQ NIPSTLLQDH ENQRLFEMLG RKCLTLATAV VQLYLALPPG AEHWTKEHCG AVCFVKDNPQ KSYFIRLYGL QAGRLLWEQE
Target Information
The Wiskott-Aldrich syndrome family of proteins share similar domain structures and are involved in signal transduction from cell surface receptors to the actin cytoskeleton. These proteins interact with various signaling molecules, including the small GTPase Cdc42 and the cytoskeletal organizing complex Arp2/3.
Wiskott-Aldrich syndrome is a rare, X-linked recessive disease characterized by immune dysregulation and microthrombocytopenia, caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein expressed exclusively in hematopoietic cells and is associated with signaling and cytoskeletal abnormalities in affected patients. A transcript variant with an alternative promoter and different 5’ UTR has been reported, though its full-length nature remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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