Thermo Fisher Scientific RUNX1/RUNX2/RUNX3 Recombinant Rabbit Monoclonal Antibody (ARC1162)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1162

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 354-453 of human RUNX1/2/3 (NP_0010018901) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RUNX1/RUNX2/RUNX3,uniProtId:Q01196-1,ncbiNodeId:9606,antigenRange:354-453,antigenLength:453,antigenImageFileName:MA5-35649_RUNX1RUNX2RUNX3_Q01196-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35649_RUNX1RUNX2RUNX3_Q01196-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:RUNX1/RUNX2/RUNX3,uniProtId:Q13950-1,ncbiNodeId:9606,antigenRange:354-453,antigenLength:521,antigenImageFileName:MA5-35649_RUNX1RUNX2RUNX3_Q13950-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35649_RUNX1RUNX2RUNX3_Q13950-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849549

Product Specific Information

Immunogen sequence: LPPPYPGSSQ AQGGPFQASS PSYHLYYGAS AGSYQFSMVG GERSPPRILP PCTNASTGSA LLNPSLPNQS DVVEAEGSHS NSPTNMAPSA RLEEAVWRPY

Target Information

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are welldocumented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.