Thermo Fisher Scientific FOXO3A Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:5,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1–2 µg/mL

Product Specifications

Product Specific Information

PA1-805 detects FoxO3.
PA1-805 has been successfully used in Western blot procedures.
In Western blot analysis of rat heart and lung, this antibody detects a ~71 kDa protein representing FoxO3.
The PA1-805 immunogen is a synthetic peptide corresponding to residues L N(654) V G N F T G A K Q A S S Q S W V(670) of human FOXO3.
This sequence is conserved in human, mouse, and rat.

Target Information

USP48 is a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases.
Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin.
Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.