Thermo Fisher Scientific PRX Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PRX. Recombinant protein control fragment (Product #RP-100995). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PRX,uniProtId:Q9BXM0-1,ncbiNodeId:9606,antigenRange:717-861,antigenLength:1461,antigenImageFileName:PA5-51646_PRX_Q9BXM0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51646_PRX_Q9BXM0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646041

Product Specific Information

Immunogen sequence: MKVPDMKLPE IKLPKVPEMA VPDVHLPEVQ LPKVSEIRLP EMQVPKVPDV HLPKAPEVKL PRAPEVQLKA TKAEQAEGME FGFKMPKMTM PKLGRAESPS RGKPGEAGAE VSGKLVTLPC LQPEVDGEAH VGVPSLTLPS VELDL

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 68%.

Target Information

Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.