Thermo Fisher Scientific FAT1 Polyclonal Antibody
Human FAT1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:1,000–1:2,500 희석 범위에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 세포 접착 및 신호전달 연구에 적합.
- 카탈로그번호
- PA551647
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAT1. Recombinant protein control fragment (Product #RP-101001). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.40 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641515 |
Product Specific Information
Immunogen sequence:
DGLGAKVSFH SLRITATDGE NFATPLYINI TVAASHKLVN LQCEETGVAK MLAEKLLQAN KLHNQGEVED IFFDSHSVNA HIPQFRSTLP TGIQVKENQP VGSSVIFMNS TDLDTGFNGK LVYAVSGGNE DSCFMIDMET GM
- Highest antigen sequence identity to orthologs:
- Mouse: 85%
- Rat: 85%
Target Information
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during development.
The gene product belongs to the cadherin superfamily, characterized by cadherin-type repeats, and includes:
- 34 tandem cadherin-type repeats
- 5 EGF-like repeats
- 1 laminin A-G domain
It is highly expressed in fetal epithelia and likely functions as an adhesion molecule and/or signaling receptor, playing important roles in developmental processes and cell communication.
Transcript variants from alternative splicing or promoter usage exist but are not fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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