Thermo Fisher Scientific CD8b Monoclonal Antibody (CA15.4G2)
개의 CD8 베타 세포 표면 항원을 인식하는 단클론 항체로, 세포독성/억제 T 림프구 연구에 적합합니다. IHC(F), Flow Cytometry, Immunoprecipitation에 사용 가능하며, 비결합(Unconjugated) 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CA15.4G2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Tissue culture supernatant |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745399 |
Product Specific Information
This antibody recognizes the canine CD8 beta cell surface antigen, expressed by cytotoxic/suppressor T lymphocytes that interact with MHC Class I expressing targets.
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor to recognize antigens presented by antigen-presenting cells (APCs) in the context of class I MHC molecules. The functional coreceptor can be a homodimer of two alpha chains or a heterodimer of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms, with multiple alternatively spliced transcript variants encoding distinct membrane-associated or secreted isoforms. A pseudogene located on chromosome 2 has also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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