Thermo Fisher Scientific CD147 Monoclonal Antibody (M036)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Clone M036 mouse monoclonal antibody detects a 38–58 kDa protein on SDS-PAGE immunoblots of human BEAS, NCIH28, NCI-H1299, LNCaP, and A431 cells, as well as human brain tissues.
The antibody is suitable for Western blot, immunoprecipitation, ELISA capture, and immunocytochemistry.

Target Information

CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein involved in spermatogenesis, embryo implantation, neural network formation, and tumor progression.
CD147 belongs to the immunoglobulin superfamily and is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It plays roles in cell surface expression of monocarboxylate transporter proteins, extracellular matrix metalloproteinases, regulation of integrin functions, and is important for cell development, activation, fetal development, and retinal function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.