Thermo Fisher Scientific HGF Polyclonal Antibody
Human HGF 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 최적화됨. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 예측 반응성은 다양한 종에 높음. 세포 성장 및 형태형성 연구용으로 적합하며 연구용으로만 사용.
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Thermo Fisher Scientific HGF Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human HGF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792468 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (91%), Rat (90%), Dog (93%), Cat (91%), Rabbit (93%), Chicken (82%), Bovine (92%).
- Positive Control: Huh-7, HepG2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Hepatocyte growth factor (HGF) regulates cell growth, motility, and morphogenesis via activation of a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Secreted by mesenchymal cells, HGF acts as a multifunctional cytokine on epithelial cells, playing a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and cleaved by serine proteases into a 69-kDa alpha-chain and a 34-kDa beta-chain, linked by a disulfide bond to form the active heterodimeric molecule. Although belonging to the plasminogen subfamily of S1 peptidases, HGF has no detectable protease activity. Alternative splicing produces multiple transcript variants encoding different isoforms.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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