Thermo Fisher Scientific PRDX3 Polyclonal Antibody
인간 PRDX3 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific PRDX3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Peroxiredoxin 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792470 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
- Centrifuge briefly prior to opening the vial.
Target Information
Peroxiredoxin (Prx) is a family of peroxidases involved in cell proliferation, differentiation, and apoptosis. Mammalian Prx proteins (approximately 50 isoforms) contain active site cysteine residues and exhibit thiol-specific antioxidant activity.
Mammalian Prxs are classified into:
- Typical 2-Cys Prx
- Atypical 2-Cys Prx
- 1-Cys Prx
Except for Prx VI (1-Cys subgroup), other 2-Cys Prxs show thioredoxin-dependent peroxidase activity using thioredoxin, thioredoxin reductase, and NADPH.
Mammalian Prxs have molecular sizes of 20–30 kDa and distinct subcellular localizations:
- Prx I, II, VI: Cytosol
- Prx III: Mitochondria
- Prx IV: Endoplasmic reticulum and secretion
- Prx V: Peroxisome, mitochondria, and cytosol
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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