Thermo Fisher Scientific NMDAR1 Recombinant Rabbit Monoclonal Antibody (JM11-26)
NMDAR1 단백질을 인식하는 재조합 토끼 단일클론 항체로, WB, IHC, ICC, Flow Cytometry 등 다양한 응용 가능. 고순도 Protein A 정제, HEK293 발현 시스템 기반. 신경세포막 단백질 검출에 적합하며 연구용으로 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM11-26 |
| Immunogen | Synthetic peptide within human NMDAR1 (aa 870–910) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911609 |
Product Specific Information
- Positive Control: N2A, SHG-44, SH-SY5Y, mouse brain tissue, rat brain tissue
- Subcellular Location: Cell membrane, postsynaptic cell membrane, postsynaptic density
Target Information
NMDAR1 encodes a protein that is a critical subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. These receptors are heteromeric protein complexes forming ligand-gated ion channels. NMDAR1 subunits play a key role in synaptic plasticity, which underlies memory and learning. Expression of different isoforms may contribute to functional diversity, and alternatively spliced variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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