Thermo Fisher Scientific DRD1 Recombinant Rabbit Monoclonal Antibody (JM10-93)
DRD1 단백질을 인식하는 재조합 토끼 모노클로날 항체로, WB, IHC, ICC/IF에 적합. 인간, 마우스, 랫트 반응성. 고순도 Protein A 정제, 1 mg/mL 농도. 세포막 및 소포체막 위치 검출에 유용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM10-93 |
| Immunogen | Synthetic peptide within C-terminal human DRD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911608 |
Product Specific Information
- Positive Control: Mouse kidney tissue lysates, 293T, N2A, SH-SY5Y, mouse brain tissue, rat brain tissue
- Subcellular Location: Cell membrane, Endoplasmic reticulum membrane
Target Information
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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