Thermo Fisher Scientific Phospho-SAR1A (Thr139) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SAR1A(Accession Q9NR31), corresponding to amino acid residues around phosphorylated Thr139. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SAR1A,uniProtId:Q9NR31-1,ncbiNodeId:9606,antigenRange:139,antigenLength:198,antigenImageFileName:PA5-105081_SAR1A_Q9NR31-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105081_SAR1A_Q9NR31-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816554

Product Specific Information

Antibody detects endogenous levels of SAR1A only when phosphorylated at Thr139.

Target Information

Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.