Thermo Fisher Scientific SUZ12 Recombinant Rabbit Monoclonal Antibody (7H26L21)
SUZ12 단백질을 타깃으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, ICC/IF, IP, ChIP, RIP 등 다양한 응용에 사용 가능. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션으로 생산됨.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| Immunoprecipitation (IP) | 1:25 |
| ChIP assay (ChIP) | 2.5 µg/1x10⁶ cells |
| RNA Immunoprecipitation (RIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Cynomolgus monkey, Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7H26L21 |
| Immunogen | Protein corresponding to human SUZ12 [aa545–aa725] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2688042 |
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, Pig, and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
SUZ12 (polycomb protein SUZ12) is a zinc finger gene involved in chromosomal translocations reported in endometrial stromal sarcoma, resulting in fusion with JAZF1.
It is a component of the PRC2/EED-EZH2 complex, which methylates histone H3 at Lys-9 (H3K9me) and Lys-27 (H3K27me), leading to transcriptional repression. The encoded protein contains a zinc finger domain in the C-terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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