Thermo Fisher Scientific EZH2 Recombinant Rabbit Monoclonal Antibody (8H32L43)
EZH2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 최적화됨. Expi293 시스템에서 생산되어 높은 특이성과 재현성을 제공. 단백질 A로 정제된 액상 형태로 제공되며, 4°C 보관 가능. 인간 및 다른 종에도 반응 예측됨.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8H32L43 |
| Immunogen | Protein corresponding to human EZH2 (aa156–aa265) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2689469 |
Product Specific Information
This antibody is predicted to react with Monkey, Rat, Horse, and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal production candidates.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG proteins form multimeric complexes that maintain transcriptional repression across cell generations.
EZH2 interacts with embryonic ectoderm development protein, VAV1 oncoprotein, and X-linked nuclear protein. It may play roles in hematopoietic and central nervous system development.
Mutations in EZH2 are associated with Weaver syndrome (WVS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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