Thermo Fisher Scientific MALT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:25-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100

-

Immunocytochemistry (ICC/IF)

1:100

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide derived from internal region of human MALT1 protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_2549949

Product Specific Information

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil or B cell lymphoma.

Target Information

MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.