Thermo Fisher Scientific MALT1 Polyclonal Antibody
MALT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 내부 유래 합성 펩타이드로부터 제작되었으며, 비결합(Unconjugated) 형태의 액상 제품. 항원 회복 시 citrate buffer 사용 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:25–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from internal region of human MALT1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_2549949 |
Product Specific Information
Heat-mediated antigen retrieval is recommended prior to staining, using a 10 mM citrate buffer (pH 6.0) for 10 minutes, followed by cooling at room temperature for 20 minutes.
After antigen retrieval, incubate samples with primary antibody for 30 minutes at room temperature.
A suggested positive control is tonsil or B cell lymphoma.
Target Information
MALT1/Paracaspase (MALT1) is a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000).
MALT1 is a caspase-like protein containing an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain.
It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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