Thermo Fisher Scientific Human ROR2, GST Tag Recombinant Protein

Thermo Fisher Scientific Human ROR2, GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, spin prior to use.
• Aliquoting is not recommended for 5 µg, 10 µg, and 20 µg sizes; use directly from original packaging.
• For larger sizes, aliquoting may reduce freeze/thaw cycles (avoid aliquots below 20 µL).
• Do not store diluted kinase.
• Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.
• Protein Form: Cytoplasmic

Target Information

ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a type I transmembrane protein belonging to the ROR subfamily of cell surface receptors. It is involved in early chondrocyte and cartilage formation, as well as growth plate development.
Expression is high during embryonic development and decreases significantly by day 16, with minimal levels in adult tissues.

Defects in ROR2 are associated with:

• Brachydactyly type B1 (BDB1): Autosomal dominant skeletal disorder causing hypoplasia/aplasia of distal phalanges and nails.
• Robinow syndrome (RRS): Autosomal recessive disorder characterized by skeletal dysplasia, limb bone shortening, spinal defects, brachydactyly, and facial dysmorphia.

Protein Domains:

• Frizzled (FZ) domain
• Immunoglobulin-like C2-type domain
• Kringle domain

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.