Thermo Fisher Scientific AMPK alpha 2 Polyclonal Antibody
AMPK alpha 2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunoprecipitation에 적합하며, Human 및 Mouse 반응성. 에너지 대사 연구 및 AMPK 신호전달 분석에 유용. 항원 친화 크로마토그래피로 정제된 고품질 항체.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–8 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 350 and 400 of human 5′-AMP-activated Protein Kinase, catalytic Alpha-2 chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Pig and Orangutan
Target Information
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK).
AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits.
It acts as an energy-sensing enzyme that monitors cellular energy status.
In response to metabolic stress, AMPK becomes activated, phosphorylating and inactivating acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), key enzymes in fatty acid and cholesterol biosynthesis.
Mouse studies indicate that this catalytic subunit may regulate insulin sensitivity and maintain myocardial energy homeostasis during ischemia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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