Thermo Fisher Scientific AMPK alpha 2 Polyclonal Antibody
Rabbit polyclonal antibody targeting AMPK alpha 2 catalytic subunit. Validated for Western blot and immunoprecipitation. Supplied as liquid, unconjugated form at 1 mg/mL concentration. Recommended storage at 4°C, shelf life 1 year.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–8 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 350 and 400 of human 5'-AMP-activated Protein Kinase, catalytic Alpha-2 chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Pig and Orangutan
Target Information
The protein encoded by this gene is a catalytic subunit of AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. AMPK acts as an energy-sensing enzyme that monitors cellular energy status. Upon activation under metabolic stress, AMPK phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), key enzymes in fatty acid and cholesterol biosynthesis. Mouse studies suggest this subunit regulates insulin sensitivity and myocardial energy homeostasis during ischemia.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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