Thermo Fisher Scientific XRCC2 Polyclonal Antibody
Rabbit polyclonal antibody against XRCC2 for detection in WB and IHC applications. Reacts with human and mouse samples. Affinity purified, unconjugated, supplied in liquid form. Ideal for DNA repair and chromosome stability research.
- 카탈로그번호
- PA5119832
- 판매단위
- pk
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Applications
Western Blot (WB)
Immunohistochemistry (Paraffin) (IHC (P))
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human XRCC2 aa 1–200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2913404 |
Product Specific Information
- Positive Control: Mouse brain tissue lysates, human kidney tissue lysates, mouse testis tissue
- Subcellular Location: Nucleus, centrosome
Target Information
The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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