Thermo Fisher Scientific Fatty Acid Binding Protein 4 (FABP4) Monoclonal Antibody (FABP4/4422)
인간 FABP4 단백질을 인식하는 Mouse IgG1 단일클론 항체로, IHC 및 Peptide Array 등 다양한 분석에 사용 가능. 지방산 결합 단백질 연구에 적합하며, 4°C 보관 시 24개월 안정성 유지. 단백질 A/G로 정제된 액상 형태.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | - |
| Peptide Array (Array) | Assay-dependent | - |
| Immunoelectrophoresis (IE) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FABP4/4422 |
| Immunogen | Recombinant fragment (around aa1–132) of human FABP4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is stable for 24 months.
- Positive Control: Human adipose tissue
- Cellular Localization: Cytoplasm, Nucleus
- Specificity Comments:
Fatty acid-binding proteins (FABPs) are a family of homologous, cytoplasmic proteins expressed in a tissue-specific manner. They play a key role in lipid and carbohydrate metabolism by mediating fatty acid and hydrophobic ligand uptake, transport, and targeting within tissues.
FABPs are expressed in various tissues: adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP), muscle and heart (H-FABP), intestine (I-FABP), liver (L-FABP), myelin (M-FABP), and testis (T-FABP).
The human A-FABP gene maps to chromosome 8q21.13 and encodes a 132 amino acid protein comprising approximately 1% of total cytosolic protein in human adipose tissue.
Target Information
FABP4 belongs to the fatty acid binding protein (FABP) family. FABPs contribute to the transport of fatty acids and other lipids in various cellular pathways.
FABP4 is expressed in adipocytes, macrophages, monocyte-derived dendritic cells, and myoepithelial cells, delivering long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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