Thermo Fisher Scientific CK2 alpha-2 Monoclonal Antibody (1E1)
Thermo Fisher Scientific의 CK2 alpha-2 Monoclonal Antibody (1E1)은 CSNK2A2 단백질을 인식하는 마우스 IgG1 항체로, WB, Flow Cytometry, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Flow Cytometry (Flow) | 1:200–1:400 | - |
| ELISA | 1:10,000 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E1 |
| Immunogen | Purified recombinant fragment of human CSNK2A2 (amino acids 194–350) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2538533 |
Product Specific Information
MA5-17062 targets CSNK2A2 in FACS, indirect ELISA, and WB applications, showing reactivity with human and mouse samples.
The immunogen is a purified recombinant fragment of human CSNK2A2 (amino acids 194–350) expressed in E. coli.
MA5-17062 detects CSNK2A2, which has a predicted molecular weight of approximately 41.2 kDa.
Target Information
Casein kinase II (CK2) is a protein serine/threonine kinase found in all eukaryotic cells, indicating fundamental cellular functions.
The holoenzyme is a tetramer containing two alpha or alpha-prime subunits (or one of each) and two beta subunits. The alpha subunit acts as the catalytic unit, while the function of beta subunits remains unclear.
CK2 can phosphorylate several intracellular signaling proteins involved in tumor suppression (p53, PTEN) and tumorigenesis (myc, jun, NF-κB). It also influences Wnt signaling via β-catenin phosphorylation and PI3K signaling via Akt phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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