Thermo Fisher Scientific Bestrophin 2 Polyclonal Antibody
Thermo Fisher Scientific의 Bestrophin 2 폴리클로날 항체는 마우스 및 랫트 시료에 반응하며 Western blot과 IHC에 적합합니다. 합성 펩타이드 항원을 사용하여 제작되었으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- OSB00059W-100UL
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from amino acids 250–300 of mouse Bestrophin 2 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term; for long-term storage, store at −20 °C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Bestrophin 2.
Target Information
Bestrophin 2 (Best2) forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene belongs to the bestrophin family of anion channels, sharing conserved exon–intron boundaries but distinct 3′ ends. Bestrophins are transmembrane proteins rich in aromatic residues, including an invariant Arg–Phe–Pro motif.
Mutations in the Best2 gene are linked to vitelliform macular dystrophy. The gene is mainly expressed in retinal pigment epithelium and colon.
Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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