Thermo Fisher Scientific SDHA Recombinant Rabbit Monoclonal Antibody (JM10-83)
SDHA 단백질을 표적하는 재조합 토끼 단클론 항체로, WB, IHC, ICC, Flow 등 다양한 응용에 적합. 높은 특이성과 민감도, 로트 간 일관성 보장. 인간, 마우스, 랫, 제브라피시 반응성. 장기 보관 시 -20°C 권장.
- 카탈로그번호
- MA532598
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM10-83 |
| Immunogen | Synthetic peptide within Human SDHA (aa 581–624) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809875 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex consists of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane.
Mutations in this gene are associated with mitochondrial respiratory chain deficiency, known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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