Thermo Fisher Scientific Growth Hormone Recombinant Rabbit Monoclonal Antibody (JM108-09)
Recombinant rabbit monoclonal antibody targeting human growth hormone. Validated for WB and IHC (P). Offers high specificity, lot-to-lot consistency, and animal origin–free formulation. Supplied as liquid, 1 mg/mL, Protein A purified, stored at 4°C or ...
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM108-09 |
| Immunogen | Synthetic peptide within Human Growth Hormone (aa 72–106) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809881 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin–free formulation
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
Human growth hormone (hGH) belongs to the somatotropin/prolactin family, essential for growth regulation. The GH1 gene, located on chromosome 17, forms part of a locus with four related genes sharing high sequence identity. Alternative splicing yields isoforms of 19–24 kDa. hGH is secreted by pituitary somatotroph cells and acts via cytokine receptor family members to stimulate IGF-1 secretion, muscle differentiation, amino acid uptake, and protein synthesis. Mutations or deletions in GH1 can lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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