Thermo Fisher Scientific TIMM8A Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 TIMM8A 단백항체로 Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제된 고순도 제품. 미토콘드리아 단백질 수입 및 삽입 관련 연구용. 장기 보관은 -20°C에서 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human TIMM8A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720163 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.
Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.
Acts as a chaperone-like protein that protects hydrophobic precursors from aggregation and guides them through the mitochondrial intermembrane space.
The TIMM8–TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1, and SLC25A13/ARALAR2, while the predominant TIMM9–TIMM10 70 kDa complex mediates the import of many more proteins.
Probably necessary for normal neurologic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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