Thermo Fisher Scientific KBTBD3 Polyclonal Antibody
Thermo Fisher Scientific의 KBTBD3 Polyclonal Antibody는 인간 KBTBD3 단백질에 특이적으로 반응하는 토끼 IgG 항체입니다. IHC(P)에서 1:20~1:50 희석 비율로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KBTBD3. Recombinant protein control fragment (Product #RP-97514) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642893 |
Product Specific Information
Immunogen sequence:
IMDAIKCVQG SGGLFPDARP STTEKYIFIH KTEENGENQY TFCYNIKSDS WKILPQSHLI DLPGSSLSSY GEKIFLTGGC KGKCCRTVRL HIAESYHDAT DQTWCY
- Highest antigen sequence identity to orthologs:
- Mouse: 94%
- Rat: 94%
Target Information
The BTB (Broad-Complex, Tram track and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers.
Proteins containing BTB domains are involved in transcriptional regulation via control of chromatin structure and function.
KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein containing:
- One BACK (BTB/Kelch associated) domain
- One BTB (POZ) domain
- Five kelch repeats
The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
Chromosome 11 is associated with genetic disorders such as Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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