Thermo Fisher Scientific EHD2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:2,500-1:5,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human EHD2. Recombinant protein control fragment (Product #RP-98852). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EHD2,uniProtId:Q9NZN4-1,ncbiNodeId:9606,antigenRange:388-476,antigenLength:543,antigenImageFileName:PA5-61497_EHD2_Q9NZN4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61497_EHD2_Q9NZN4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640940

Product Specific Information

Immunogen sequence: HDIAKLMPLL RQEELESTEV GVQGGAFEGT HMGPFVERGP DEAMEDGEEG SDDEAEWVVT KDKSKYDEIF YNLAPADGKL SGSKAKTWM

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.

Target Information

This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.