Thermo Fisher Scientific EHD2 Polyclonal Antibody
EHD2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC(P), ICC/IF에 적합합니다. 인간 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. PBS(40% glycerol) 용액 형태로 제공되며, 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EHD2. Recombinant protein control fragment (Product #RP-98852) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640940 |
Product Specific Information
Immunogen sequence:
HDIAKLMPLL RQEELESTEV GVQGGAFEGT HMGPFVERGP DEAMEDGEEG SDDEAEWVVT KDKSKYDEIF YNLAPADGKL SGSKAKTWM
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 93%
Target Information
This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus, and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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