Thermo Fisher Scientific RND2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.

Target Information

The Ras p21 family of guanine nucleotide proteins plays a key role in signal transduction pathways and is frequently mutated in human malignancies. Ras proteins (H-, K-, and N-Ras p21) belong to a larger superfamily that includes Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A, and Ral B, which share approximately 50% amino acid homology with Ras. The mammalian Rho proteins (Rho A, B, C, G, 7, and 8) exhibit about 30% homology and are expressed in various cell types. Members of the Ras superfamily contain a carboxy-terminal CAAX sequence (C: cysteine; A: aliphatic amino acid; X: any amino acid), which is critical for proper localization and function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.