Thermo Fisher Scientific Relaxin 2 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).

Target Information

Relaxin 1 (also referred to as Relaxin or RLXH1) is a peptide hormone produced by the corpora lutea of the ovary during pregnancy in many mammalian species, including human. The secretion of the hormone into the bloodstream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, Relaxin 1 may influence the timing of parturition.

Like insulin, Relaxin 1 consists of two peptide chains, A and B, covalently linked by disulfide bonds. The two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the amino terminus. The gene encoding human Relaxin 1 maps to chromosome 9. Relaxin 2, a related protein, is selectively expressed in the ovary during pregnancy, and its gene also maps to chromosome 9.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.