Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (rKRT14/7269)
인간 KRT14 단백질을 인식하는 마우스 단클론 항체로, 편평상피세포 표지에 사용. IHC(파라핀, PFA 고정)에 적합하며, 단백질 A/G 정제. 단백질 농도 1 mg/mL, 보존제 없음. -20°C 보관, 연구용 전용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rKRT14/7269 |
| Immunogen | Recombinant human KRT14 fragment (around aa350–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, present in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs have been identified, grouped into two main classes:
- Type I (acidic polypeptides)
- Type II (basic polypeptides)
Keratin 14 (KRT14), a type I low molecular weight keratin, pairs with keratin 5 and is a marker distinguishing stratified epithelial cells from simple epithelial cells. It is useful for identifying squamous cell carcinomas and serves as a prognostic marker in breast carcinomas. Typically, epithelial cells express at least one acidic and one basic cytokeratin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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