Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (rKRT14/7290)
사람 세포 반응성을 가진 Cytokeratin 14 단클론 항체로, 편평세포암 및 상피세포 표지용으로 적합. Immunohistochemistry(PFA 및 Paraffin) 실험에 사용 가능. 단백질 A/G 정제, 보존제 무첨가, -20°C 보관.
- 카탈로그번호
- 3861MSM30P1ABX
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rKRT14/7290 |
| Immunogen | Recombinant human KRT14 fragment (around aa350–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs can be identified. Most CK family members fall into two classes: type I (acidic polypeptides) and type II (basic polypeptides).
Keratin 14 belongs to the type I subfamily of low molecular weight keratins and typically pairs with keratin 5. It distinguishes stratified epithelial cells from simple epithelial cells and is useful for identifying squamous cell carcinomas. It is also considered a prognostic marker in breast carcinomas.
At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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