Thermo Fisher Scientific KLF17/ ZNF393 Monoclonal Antibody (PCRP-KLF17-1G2)
KLF17/ZNF393 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow cytometry, IP, Peptide array 등 다양한 응용에 적합. 단백질 발현 조절 및 암 전이 연구에 활용 가능. PBS 용액 형태, 보존제 없음, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Immunoprecipitation (IP) | 1–2 µg |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-KLF17-1G2 |
| Immunogen | Recombinant full-length human KLF17 protein (UniProt ID: Q5JT82-1, amino acids 1–389) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
Target Information
KLF17 is a transcription repressor that binds to promoter regions of target genes, suppressing their expression. It acts as a negative regulator of epithelial-mesenchymal transition (EMT) and metastasis in breast cancer by binding to the 5′-CACCC-3′ motif in the promoter of ID1, a key metastasis regulator. KLF17 may also function as a germ cell-specific transcription factor involved in spermatid differentiation and oocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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