Thermo Fisher Scientific KLF17/ ZNF393 Monoclonal Antibody (PCRP-KLF17-1G2)
KLF17/ZNF393 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow cytometry, IP 등 다양한 응용에 사용 가능. Human 시료 반응성, Protein A/G 정제, PBS 버퍼에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Immunoprecipitation (IP) | 1–2 µg |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-KLF17-1G2 |
| Immunogen | Recombinant full-length human KLF17 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. It acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically, it binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and represses its expression. KLF17 may also function as a germ cell-specific transcription factor, playing important roles in spermatid differentiation and oocyte development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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