Thermo Fisher Scientific Cell-Surface Vimentin (CSV) Monoclonal Antibody (84-1), PE

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 10–100 µg/mL

Flow Cytometry (Flow)

• Tested Dilution: 1×10⁶ cells / 50 µL

Product Specifications

Additional Formats

• Unconjugated
• APC
• Biotin
• FITC
• Texas Red
• Request custom conjugation

Target Information

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in intracellular protein transport between the nucleus and plasma membrane. Vimentin, along with desmin, is expressed during early cellular development and later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by serving as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin by protein kinase leads to filament breakdown and cytoskeletal rearrangement, facilitating cholesterol transport to mitochondria and enhancing steroid synthesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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