Thermo Fisher Scientific Cell-Surface Vimentin (CSV) Monoclonal Antibody (84-1), Texas Red
인간 세포 표면 비멘틴(CSV)을 인식하는 Mouse monoclonal 항체로, Texas Red 형광으로 표지됨. ICC/IF 및 Flow Cytometry에 적합하며, 595/613 nm의 Excitation/Emission 특성을 가짐. Affinity chromatography로 정제되어 PBS(pH 7.4) 용액에 보존됨.
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- H00007431-MT08
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- pk
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10–100 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 1×10⁶ cells / 50 µL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 84-1 |
| Immunogen | Human recombinant vimentin |
| Conjugate | Texas Red |
| Excitation / Emission Max | 595 / 613 nm |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | 4°C, store in dark |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved in intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFPs, vimentin is expressed along with desmin during early cellular development, and later replaced by tissue-specific IFPs.
Vimentin plays a role in steroid synthesis by acting as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin leads to intermediate filament breakdown and cytoskeletal rearrangements that enhance cholesterol transport to mitochondria, promoting steroid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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