Thermo Fisher Scientific PTBP1 Monoclonal Antibody (1)
PTBP1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A로 정제된 액상 항체로, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | 39 publications |
| Immunohistochemistry (IHC) | – | 3 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | 10 publications |
| Flow Cytometry (Flow) | 3–5 µg/1×10⁶ cells | 2 publications |
| Immunoprecipitation (IP) | Assay-dependent | 11 publications |
| ChIP assay (ChIP) | – | 2 publications |
| RNA Immunoprecipitation (RIP) | Assay-dependent | 7 publications |
| In Situ Hybridization (ISH) | – | 1 publication |
| Miscellaneous PubMed (Misc) | – | 1 publication |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat, Virus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1 |
| Immunogen | Recombinant human PTB protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533082 |
Product Specific Information
This antibody reacts with the C-terminus of the human and rodent PTB protein.
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing, mRNA metabolism, and transport. Some hnRNPs shuttle between the nucleus and cytoplasm. The encoded protein contains four quasi-RNA recognition motif (RRM) domains that bind RNA, recognizing intronic polypyrimidine tracts required for pre-mRNA splicing. It may promote U2 snRNP binding to pre-mRNAs and is localized in the nucleoplasm and perinucleolar structures. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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