Thermo Fisher Scientific PKP1 Monoclonal Antibody (10B2)
PKP1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, ICC/IF, IHC(F), IP에 사용 가능. Human에 반응하며 Protein A로 정제된 액상 형태. Plakophilin-1 연구 및 세포 접합 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 2 publications |
| Immunoprecipitation (IP) | 2 µg | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10B2 |
| Immunogen | N-terminus of Human plakophilin-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533086 |
Target Information
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been identified for this gene.
[Provided by RefSeq, Jul 2010]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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